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The drug does cause weight losstheres not much question about that, says Neal Barnard, M.D., FACC, president of the Physicians Committee for Responsible Medicine

Cardiovascular and metabolic signals Resting heart rate increased by about 5-10 bpm on average

The Lancet , 399(10326), 2192-2203

But change is afoot

However, this remains a theoretical concern, and the clinical significance of this effect on iron status is unproven and requires further research

Before medication, I was 232 pounds

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